P-190: Pregnancy Outcomes in Women with Polycystic Ovary Syndrome Compared with Normal Women

Background: Polycystic ovary syndrome (PCOS) is a common reproductive disorder associated with many characteristic features, including hyperandrogenaemia, insulin resistance and obesity which may have significant implications for pregnancy outcomes and long-term health of the woman. It has an incidence ranging from 5 to 10%. Materials and Methods: This study is conducted to evaluate the pregnancy and perinatal outcome in women with PCOS. Pregnancy outcomes in 208 women with PCOS and were compared with 240 normal women. Results: Women with PCOS demonstrated a significantly higher risk of developing gestational diabetes (133 in PCOS groups vs. 98 in normal group, p=0.00), pregnancy-induced hypertension and preeclampsia (67 in PCOS groups vs. 21 in normal group, p=0.01) and preterm labor (22 in PCOS groups vs. 14 in normal group p=0.01). Furthermore, women with PCOS seem to experience increased risk of cesarean delivery than normal group. There was no increased risk of congenital anomalies. Conclusion: Women with PCOS are at increased risk of pregnancy complications. Pre-pregnancy, antenatal and intrapartum care should be aimed at reducing these risks.